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J Clin Res Pediatr Endocrinol. 2019 Jan 3. doi: 10.4274/jcrpe.0274. [Epub ahead of print]

Early menarche is a risk factor of short stature in young Korean female: Epidemiologic study

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Department of Pediatrics, Korea Cancer Center Hospital, Seoul 139-706, Republic of Korea



We investigated the association between age at menarche and adult height (and body mass index; BMI) in young Korean female. We also investigated whether early menarche (<12years) is a risk factor of short stature and obesity in young Korean female.


We analyzed data for 1148 female aged 18–30 years (612 pairs of mothers and daughters) from the 6th Korea National Health and Nutrition Examination Survey (KNHANES IV) (2013–2015).


Among 1148 female, 256(22.3%) female had early menarche. Female grew approximately 0.445 cm shorter when menarche occurred 1 year earlier. The prevalence of short stature (≤153cm) and obesity(BMI≥25) was higher in female with early menarche compared with later menarche(short stature: 10.5% vs. 6.4%, obesity; 20.7% vs. 13.1%, all P < 0.001). In multivariate regression, the odds ratio (OR) of short stature was 2.62(95%CI 1.26-5.44) adjusting for current age and mother’s height. However, the OR of obesity was 1.74(0.98-3.07) after adjusting for age and mother’ BMI.


The final height for female is influenced by age of menarche. Early menarche increased the risk of adult short stature in young Korean female.


Early menarche; short stature; adult height; Obesity; KNHANES

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