Abstract
A 24-year-old man with dilated aortic root and vascular type Ehlers-Danlos syndrome underwent aortic root replacement with a stentless bioprosthesis. A year later he developed aortic valve endocarditis necessitating a redo valve replacement. Excised valve tissue grew fungus Purpureocillium lilacinum. Over a period of 4 years the case was further complicated with mycotic aneurysm of the infrarenal aorta, a retroperitoneal abscess (treated surgically), a right common iliac aneurysm, right lower limb emboli (femoral embolectomy and left-to-right femoral bypass was performed), 2 false aneurysms of the ascending aorta with a large mobile mass attached to the anterior aneurysm, and brain abscesses.
Copyright © 2019 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.
MeSH terms
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Aneurysm, False / diagnostic imaging
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Aneurysm, False / etiology
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Aneurysm, False / therapy
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Aneurysm, Infected / diagnostic imaging
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Aneurysm, Infected / etiology*
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Aneurysm, Infected / therapy
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Antifungal Agents / therapeutic use
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Aortic Valve Insufficiency / complications
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Aortic Valve Insufficiency / diagnostic imaging
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Aortic Valve Insufficiency / surgery*
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Bioprosthesis / adverse effects*
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Chest Pain / diagnosis
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Chest Pain / etiology
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Combined Modality Therapy
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Disease Progression
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Ehlers-Danlos Syndrome / complications*
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Ehlers-Danlos Syndrome / diagnosis
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Endocarditis / complications
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Endocarditis / etiology
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Endocarditis / microbiology
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Endocarditis / therapy
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Fatal Outcome
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Heart Valve Prosthesis Implantation / adverse effects*
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Heart Valve Prosthesis Implantation / methods
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Humans
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Male
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Prosthesis-Related Infections / diagnostic imaging
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Prosthesis-Related Infections / surgery*
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Rare Diseases
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Reoperation / methods
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Risk Assessment
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Young Adult