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World Neurosurg. 2019 Jan;121:239-242. doi: 10.1016/j.wneu.2018.10.028. Epub 2018 Oct 12.

Natural Course of Myxopapillary Ependymoma: Unusual Case Report and Review of Literature.

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Sultan Abdulhamid Training and Research Hospital, Department of Neurosurgery, Istanbul, Turkey. Electronic address:
Craniospinal Surgery Center, Ankara, Turkey.
Anadolu Medical Center Hospital, Department of Neurosurgery, Kocaeli, Turkey.
Pamukkale University Hospital, Department of Neurosurgery, Denizli, Turkey.



Spinal cord ependymomas are the most frequent primary intramedullary tumors of the cord in middle age (40-60 years of age). Myxopapillary ependymomas are low-incidence tumors and occur in the cauda equina and conus medullaris. They are typically described as fleshy, sausage-shaped, vascular lesions.


In this report, we present a 36-year-old woman who was seen in another hospital with complaints of back pain radiating into both legs 5 years ago. Magnetic resonance imaging (MRI) examinations revealed a lesion releated to the spinal cord. At that point, the patient refused the proposed surgical treatment. Five years later, the patient was referred to our clinic with advancement of the complaint to paraparesis. The new MRI showed an intradural mass at the level of T11 and S1. We performed a total intradural tumor resection. Histopathologic examination revealed a myxopapillary ependymoma.


Myxopapillary ependymomas grow slowly and are well defined by MRI. Advancements in radiologic technology and surgical equipment have allowed this tumor type to be treated successfully. Unfortunately, if untreated, these lesions have poor prognosis and result in clinical symptoms such as paraparesis. Surgical treatment of these lesions using total resection was performed total resection and was associated with an excellent postoperative outcome. We highlight the natural course of myxopapillary ependymomas.


Intradural; Magnetic resonance imaging; Myxopapillary ependymoma; Spinal cord tumor

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