Eosinophilic granuloma of the spine involving C1 and pulmonary infiltration in young children - Presentation of two cases with a follow-up over 10 years including review of the literature

J Orthop. 2018 Aug 16;15(3):808-811. doi: 10.1016/j.jor.2018.08.012. eCollection 2018 Sep.

Abstract

Objectives: The incidence of spinal eosinophilic granuloma in children is low.

Methods: Clinical case presentation of two children (♀ 18 months old, ♂ 16 months old) complaining of acute torticollis. Follow-up period was 11 years in the female patient and 13 years in the male patient.

Results: The diagnostics certified a spinal eosinophilic granuloma: the girl had a multilevel spinal disease including the atlas, the boy a thoracic and pulmonary manifestation. Both were treated with chemotherapy with good clinical results.

Conclusions: Overall, the above described is a very rare clinical entity. However, persisting torticollis in children should be clearly diagnosed.

Keywords: Atlas; Chemotherapy; Children; Eosinophilic granuloma; Spine.

Publication types

  • Review