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Page 1
Safety Assessment of 2-Amino-3-Hydroxypyridine as Used in Cosmetics.
Burnett CL, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler DC, Marks JG Jr, Shank RC, Slaga TJ, Snyder PW, Gill LJ, Heldreth B. Burnett CL, et al. Int J Toxicol. 2020 Sep;39(2_suppl):91S-97S. doi: 10.1177/1091581820952376. Int J Toxicol. 2020. PMID: 32975151 Review.
The Expert Panel for Cosmetic Ingredient Safety (Panel) reviewed the safety of 2-Amino-3-Hydroxypyridine, which is reported to function as an oxidative hair dye ingredient. The Panel reviewed relevant animal and human data provided in this safety assessment, and con …
The Expert Panel for Cosmetic Ingredient Safety (Panel) reviewed the safety of 2-Amino-3-Hydroxypyridine, which is reported to …
[Complex application 2-ethyl-6-methyl-3-hydroxypyridine-succinate and vinpocetine in cerebrovascular disorder.].
Solovyeva EY, Karneev AN, Chekanov AV, Baranova OA, Choi IV. Solovyeva EY, et al. Zh Nevrol Psikhiatr Im S S Korsakova. 2017;117(5):103-108. doi: 10.17116/jnevro201711751103-108. Zh Nevrol Psikhiatr Im S S Korsakova. 2017. PMID: 28638040 Review. Russian.
Early use of antioxidants such as ethyl ether apovincamine acid (vinpocetine) and 2-ethyl-6-methyl-3-hydroxypyridine-succinate in the treatment of this pathology is seen as a real pathogenetically based method of correction of cerebral metabolism with cerebral vascu …
Early use of antioxidants such as ethyl ether apovincamine acid (vinpocetine) and 2-ethyl-6-methyl-3-hydroxypyridine-succinate …
Isolation of a 3-hydroxypyridine degrading bacterium, Agrobacterium sp. DW-1, and its proposed degradation pathway.
Zhao S, Hu C, Guo L, Li K, Yu H. Zhao S, et al. AMB Express. 2019 May 17;9(1):65. doi: 10.1186/s13568-019-0782-9. AMB Express. 2019. PMID: 31102032 Free PMC article.
The optimal cultivation temperature and pH for strain DW-1 with 3-hydroxypyridine were 30 C and 8.0, respectively. Under optimal conditions, strain DW-1 could completely degrade up to 1500 mg/L of 3-hydroxypyridine in 66 h. The 3-hydroxypyrid …
The optimal cultivation temperature and pH for strain DW-1 with 3-hydroxypyridine were 30 C and 8.0, respectively. Under optim …
3-Hydroxypyridine Dehydrogenase HpdA Is Encoded by a Novel Four-Component Gene Cluster and Catalyzes the First Step of 3-Hydroxypyridine Catabolism in Ensifer adhaerens HP1.
Wang H, Wang X, Ren H, Wang X, Lu Z. Wang H, et al. Appl Environ Microbiol. 2020 Sep 17;86(19):e01313-20. doi: 10.1128/AEM.01313-20. Print 2020 Sep 17. Appl Environ Microbiol. 2020. PMID: 32709720 Free PMC article.
3-Hydroxypyridine (3HP) is an important natural pyridine derivative. ...Our findings provide new insight into the catabolism of 3-hydroxypyridine in bacteria....
3-Hydroxypyridine (3HP) is an important natural pyridine derivative. ...Our findings provide new insight into the catabolism o …
Reversible Redox System of 2-Oxypyritriphyrin(1.2.1) Accompanying Interconversion between 3-Pyridone and 3-Hydroxypyridine Units.
Chong SG, Yoneda T, Ide Y, Neya S. Chong SG, et al. Chem Asian J. 2021 May 3;16(9):1077-1080. doi: 10.1002/asia.202100200. Epub 2021 Mar 31. Chem Asian J. 2021. PMID: 33713547 Free article.
To develop a system in which a pi-conjugation circuit switched by a redox reaction between 3-pyridone and 3-hydroxypyridine, a ring-contracted analog of oxypyriporphyrin, 2-oxypyritriphyrin(1.2.1) was synthesized for the first time. 2-Oxypyritriphyrin(1.2.1) contain …
To develop a system in which a pi-conjugation circuit switched by a redox reaction between 3-pyridone and 3-hydroxypyridine, a …
3-hydroxypyridine chromophores are endogenous sensitizers of photooxidative stress in human skin cells.
Wondrak GT, Roberts MJ, Jacobson MK, Jacobson EL. Wondrak GT, et al. J Biol Chem. 2004 Jul 16;279(29):30009-20. doi: 10.1074/jbc.M404379200. Epub 2004 May 7. J Biol Chem. 2004. PMID: 15133022 Free article.
Photosensitization of cultured human skin keratinocytes (HaCaT) and fibroblasts (CF3) by endogenous and synthetic 3-hydroxypyridine derivatives led to a dose-dependent inhibition of proliferation, cell cycle arrest in G2/M, and induction of apoptosis, all of which w …
Photosensitization of cultured human skin keratinocytes (HaCaT) and fibroblasts (CF3) by endogenous and synthetic 3-hydroxypyridin …
A Comparative DFT Study on the Antioxidant Activity of Some Novel 3-Hydroxypyridine-4-One Derivatives.
Dehkordi MM, Asgarshamsi MH, Fassihi A, Zborowski KK. Dehkordi MM, et al. Chem Biodivers. 2022 Mar;19(3):e202100703. doi: 10.1002/cbdv.202100703. Epub 2022 Jan 27. Chem Biodivers. 2022. PMID: 34997823
The current study on the antioxidant activity of kojic acid and 3-hydroxypyridine-4-one derivatives was performed by implementation of density functional theory calculations with the B3LYP hybrid functional and the 6-311++G** basis set in Polarizable Continuum Model …
The current study on the antioxidant activity of kojic acid and 3-hydroxypyridine-4-one derivatives was performed by implement …
Cerebroprotective Effects of 2-Ethyl-6-methyl-3-hydroxypyridine-2,6-dichlorophenyl(amino)phenylethanoic Acid in the Treatment of Purulent Meningitis.
Agarkova A, Pokrovskii M, Kolesnichenko P, Gureev V, Gudyrev O, Peresypkina A, Soldatov V, Nesterov A, Denisyuk T, Korokin M. Agarkova A, et al. Biomedicines. 2021 Mar 11;9(3):285. doi: 10.3390/biomedicines9030285. Biomedicines. 2021. PMID: 33799578 Free PMC article.
The aim of the study was to evaluate the cerebroprotective effects of a new pharmacological compound 2-ethyl-6-methyl-3-hydroxypyridine-2,6-dichlorophenyl(amino)phenylethanoic acid (EMHDPA) on the bacterial purulent meningitis in a model of experimental pneumococcal …
The aim of the study was to evaluate the cerebroprotective effects of a new pharmacological compound 2-ethyl-6-methyl-3-hydroxypyr …
Photosensitized 2-amino-3-hydroxypyridine-induced mitochondrial apoptosis via Smac/DIABLO in human skin cells.
Goyal S, Amar SK, Dwivedi A, Mujtaba SF, Kushwaha HN, Chopra D, Pal MK, Singh D, Chaturvedi RK, Ray RS. Goyal S, et al. Toxicol Appl Pharmacol. 2016 Apr 15;297:12-21. doi: 10.1016/j.taap.2016.02.022. Epub 2016 Mar 2. Toxicol Appl Pharmacol. 2016. PMID: 26933830
The popularity of hair dyes use has been increasing regularly throughout the world as per the demand of hair coloring fashion trends and other cosmetic products. 2-Amino-3-hydroxypyridine (A132) is widely used as a hair dye ingredient around the world. ...
The popularity of hair dyes use has been increasing regularly throughout the world as per the demand of hair coloring fashion trends and oth …
509 results