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Neurosci Lett. 2019 Jan 10;689:14-20. doi: 10.1016/j.neulet.2018.06.026. Epub 2018 Jun 15.

Dynamic interactions between GABAergic and astrocytic networks.

Author information

1
University of Padua, Department of Biomedical Sciences, Padua, Italy; CNR, Neuroscience Institute, Padua, Italy.
2
University of Padua, Department of Biomedical Sciences, Padua, Italy; CNR, Neuroscience Institute, Padua, Italy. Electronic address: micaela.zonta@cnr.it.

Abstract

Brain network activity derives from the concerted action of different cell populations. Together with interneurons, astrocytes play fundamental roles in shaping the inhibition in brain circuitries and modulating neuronal transmission. In this review, we summarize past and recent findings that reveal in neural networks the importance of the interaction between GABAergic signaling and astrocytes and discuss its physiological and pathological relevance.

KEYWORDS:

Astrocytes; Calcium signaling; GABA; Interneurons; Synaptic transmission

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