Biomechanics and structure of the cornea: implications and association with corneal disorders

Jiaonan Ma; Yan Wang; Pinghui Wei; Vishal Jhanji

doi:10.1016/j.survophthal.2018.05.004

Biomechanics and structure of the cornea: implications and association with corneal disorders

Surv Ophthalmol. 2018 Nov-Dec;63(6):851-861. doi: 10.1016/j.survophthal.2018.05.004. Epub 2018 May 30.

Authors

Jiaonan Ma¹, Yan Wang², Pinghui Wei³, Vishal Jhanji⁴

Affiliations

¹ Clinical College of Ophthalmology, Tianjin Medical University, Tianjin, China.
² Clinical College of Ophthalmology, Tianjin Medical University, Tianjin, China; Tianjin Eye Hospital, Tianjin Eye Institute, Tianjin Key Laboratory of Ophthalmology and Visual Science, Naikai University, Tianjin Medical University, Tianjin, China. Electronic address: wangyan7143@vip.sina.com.
³ Tianjin Eye Hospital, Tianjin Eye Institute, Tianjin Key Laboratory of Ophthalmology and Visual Science, Naikai University, Tianjin Medical University, Tianjin, China.
⁴ UPMC Eye Center, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.

PMID: 29857022
DOI: 10.1016/j.survophthal.2018.05.004

Abstract

Recent studies have shown that alterations in corneal biomechanical properties are associated with corneal pathologies, particularly corneal ectasia. Moreover, these alterations may have implications with regard to the outcomes of therapeutic modalities and corneal refractive surgeries. We address corneal anatomy and its relevance to corneal biomechanical characteristics, as well as ocular and systemic conditions associated with changes in corneal biomechanics.

Keywords: corneal anatomy; corneal biomechanics; corneal disorder.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Biomechanical Phenomena
Collagen / metabolism
Cornea* / anatomy & histology
Cornea* / physiology
Cornea* / surgery
Corneal Diseases / physiopathology*
Corneal Diseases / therapy
Humans
Orthokeratologic Procedures
Refractive Surgical Procedures

Substances

Collagen