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Methods Mol Biol. 2018;1757:163-209. doi: 10.1007/978-1-4939-7737-6_8.

A Primer for the Rat Genome Database (RGD).

Author information

1
Department of Biomedical Engineering, Medical College of Wisconsin and Marquette University, Milwaukee, WI, USA. slaulede@mcw.edu.
2
Department of Biomedical Engineering, Medical College of Wisconsin and Marquette University, Milwaukee, WI, USA.
3
Genomic Sciences and Precision Medicine Center, Medical College of Wisconsin, Milwaukee, WI, USA.
4
Department of Physiology, Medical College of Wisconsin, Milwaukee, WI, USA.

Abstract

The laboratory rat, Rattus norvegicus, is an important model of human health and disease, and experimental findings in the rat have relevance to human physiology and disease. The Rat Genome Database (RGD, http://rgd.mcw.edu ) is a model organism database that provides access to a wide variety of curated rat data including disease associations, phenotypes, pathways, molecular functions, biological processes and cellular components for genes, quantitative trait loci, and strains. We present an overview of the database followed by specific examples that can be used to gain experience in employing RGD to explore the wealth of functional data available for the rat.

KEYWORDS:

Database; Gene; Genomics; Ontology; Quantitative trait locus; Rat

PMID:
29761460
PMCID:
PMC6487669
DOI:
10.1007/978-1-4939-7737-6_8
[Indexed for MEDLINE]
Free PMC Article

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