Isotretinoin-induced urethritis versus non-gonococcal urethritis in a man who has sex with men: an open debate

Int J STD AIDS. 2018 Sep;29(10):1024-1026. doi: 10.1177/0956462418761261. Epub 2018 Mar 7.

Abstract

This is the case of a young man presenting with urethritis despite a negative infectious work-up. Careful history taking elucidated a strong correlation between symptom onset and a recent dose escalation of isotretinoin for treatment of his refractory cystic acne. The urethral symptoms quickly resolved with dose reduction, suggesting urethritis as a rare adverse reaction of isotretinoin.

Keywords: Urethritis; adverse reaction; isotretinoin; retinoid dermatitis; sexually transmitted infection.

Publication types

  • Case Reports

MeSH terms

  • Acne Vulgaris / drug therapy*
  • Adult
  • Homosexuality, Male*
  • Humans
  • Isotretinoin / adverse effects*
  • Isotretinoin / therapeutic use
  • Male
  • Urethritis / chemically induced*

Substances

  • Isotretinoin