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J Emerg Med. 2018 May;54(5):e97-e99. doi: 10.1016/j.jemermed.2018.01.029. Epub 2018 Mar 2.

Hemoptysis? Try Inhaled Tranexamic Acid.

Author information

1
Department of Emergency Medicine, Zuckerberg San Francisco General Hospital, San Francisco, California.
2
Department of Emergency Medicine, Zuckerberg San Francisco General Hospital, San Francisco, California; Department of Emergency Medicine, University of California, San Francisco, California.

Abstract

BACKGROUND:

Tranexamic acid (TXA) is a synthetic anti-fibrinolytic agent used to prevent and treat various bleeding complications. In many studies, investigators have evaluated its utility and safety orally, intravenously, and topically, but few studies have described the potential benefits of nebulized TXA.

CASE REPORT:

We present a case of massive hemoptysis treated with nebulized TXA in the emergency department (ED) that led to the cessation of bleeding and avoidance of endotracheal intubation. WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: In massive hemoptysis, rapidly available nebulized TXA may be considered a therapeutic option, serving either as primary therapy or as a bridge until other definitive therapies can be arranged.

KEYWORDS:

hemoptysis treatment; massive hemoptysis; nebulized tranexamic acid; tranexamic acid

PMID:
29502864
DOI:
10.1016/j.jemermed.2018.01.029
[Indexed for MEDLINE]

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