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Emerg Infect Dis. 2018 May;24(5). doi: 10.3201/eid2405.171747. Epub 2018 May 17.

External Quality Assessment for Zika Virus Molecular Diagnostic Testing, Brazil.

Abstract

We conducted an external quality assessment of Zika virus molecular diagnostic tests in Brazil using a new Zika virus standard. Of 15 laboratories, 73% showed limited sensitivity and specificity. Viral load estimates varied significantly. Continuous quality assurance is needed to adequately estimate risk for Zika virus-associated disease and determine patient care.

KEYWORDS:

Americas ; Brazil ; Zika virus ; diagnostics ; real-time RT-PCR ; surveillance ; vector-borne infections ; viruses

PMID:
29470164
PMCID:
PMC5938781
DOI:
10.3201/eid2405.171747
[Indexed for MEDLINE]
Free PMC Article

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