Agenesis of dorsal pancreas in a young adult: a rare cause of diabetes mellitus

BMJ Case Rep. 2018 Feb 14:2018:bcr2017223301. doi: 10.1136/bcr-2017-223301.

Abstract

Dorsal pancreatic agenesis is an extremely rare entity characterised by absence of body and tail of pancreas, while there are so many other developmental anomalies of the pancreas that have been reported. Here we report a 25-year-old young man who presented with pain in the abdomen, recurrent loose stools and hyperglycaemia. On radiological imaging study, there was complete agenesis of the dorsal pancreas except for thin stripe of tissue at the level of the uncinate process. Both exocrinedysfunction and endocrine dysfunction were present in this patient. Patient was supplemented with pancreatic enzyme preparation and insulin.

Keywords: atrophied; computed tomography; dorsal pancreatic agenesis; magnetic resonance cholangiopancreatography; pancreatic anomaly.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Cholangiopancreatography, Magnetic Resonance
  • Congenital Abnormalities / diagnostic imaging*
  • Congenital Abnormalities / drug therapy*
  • Congenital Abnormalities / pathology
  • Diabetes Mellitus, Type 1 / etiology
  • Diagnosis, Differential
  • Humans
  • Insulin / therapeutic use*
  • Male
  • Pancreas / abnormalities*
  • Pancreas / diagnostic imaging
  • Pancreas / pathology
  • Pancreatic Extracts / therapeutic use*
  • Rare Diseases / complications
  • Rare Diseases / diagnostic imaging
  • Tomography, X-Ray Computed

Substances

  • Insulin
  • Pancreatic Extracts

Supplementary concepts

  • Pancreas agenesis, dorsal