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Items: 6

1.

TRPV1 antagonists that cause hypothermia, instead of hyperthermia, in rodents: Compounds' pharmacological profiles, in vivo targets, thermoeffectors recruited and implications for drug development.

Garami A, Pakai E, McDonald HA, Reilly RM, Gomtsyan A, Corrigan JJ, Pinter E, Zhu DXD, Lehto SG, Gavva NR, Kym PR, Romanovsky AA.

Acta Physiol (Oxf). 2018 Jul;223(3):e13038. doi: 10.1111/apha.13038. Epub 2018 Feb 16.

2.

Transient Receptor Potential Vanilloid 1 Antagonists Prevent Anesthesia-induced Hypothermia and Decrease Postincisional Opioid Dose Requirements in Rodents.

Garami A, Ibrahim M, Gilbraith K, Khanna R, Pakai E, Miko A, Pinter E, Romanovsky AA, Porreca F, Patwardhan AM.

Anesthesiology. 2017 Nov;127(5):813-823. doi: 10.1097/ALN.0000000000001812.

PMID:
28806222
3.

Contributions of different modes of TRPV1 activation to TRPV1 antagonist-induced hyperthermia.

Garami A, Shimansky YP, Pakai E, Oliveira DL, Gavva NR, Romanovsky AA.

J Neurosci. 2010 Jan 27;30(4):1435-40. doi: 10.1523/JNEUROSCI.5150-09.2010.

4.

The transient receptor potential vanilloid-1 channel in thermoregulation: a thermosensor it is not.

Romanovsky AA, Almeida MC, Garami A, Steiner AA, Norman MH, Morrison SF, Nakamura K, Burmeister JJ, Nucci TB.

Pharmacol Rev. 2009 Sep;61(3):228-61. doi: 10.1124/pr.109.001263. Epub 2009 Sep 11. Review.

5.

Pharmacological blockade of the vanilloid receptor TRPV1 elicits marked hyperthermia in humans.

Gavva NR, Treanor JJ, Garami A, Fang L, Surapaneni S, Akrami A, Alvarez F, Bak A, Darling M, Gore A, Jang GR, Kesslak JP, Ni L, Norman MH, Palluconi G, Rose MJ, Salfi M, Tan E, Romanovsky AA, Banfield C, Davar G.

Pain. 2008 May;136(1-2):202-10. doi: 10.1016/j.pain.2008.01.024. Epub 2008 Mar 11.

PMID:
18337008
6.

Nonthermal activation of transient receptor potential vanilloid-1 channels in abdominal viscera tonically inhibits autonomic cold-defense effectors.

Steiner AA, Turek VF, Almeida MC, Burmeister JJ, Oliveira DL, Roberts JL, Bannon AW, Norman MH, Louis JC, Treanor JJ, Gavva NR, Romanovsky AA.

J Neurosci. 2007 Jul 11;27(28):7459-68.

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