Sucrase-isomaltase 15Phe IBS risk variant in relation to dietary carbohydrates and faecal microbiota composition

Gut. 2019 Jan;68(1):177-178. doi: 10.1136/gutjnl-2017-315841. Epub 2018 Jan 13.

Louise Thingholm¹, Malte Rühlemann¹, Jun Wang², Matthias Hübenthal¹, Wolfgang Lieb³, Matthias Laudes⁴, Andre Franke^#¹, Mauro D'Amato^#^{5

6

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¹ Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany.
² CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
³ Institute of Epidemiology and Biobank PopGen, Christian-Albrechts-University of Kiel, Kiel, Germany.
⁴ Department of Internal Medicine I, University Hospital S-H (UKSH, Campus Kiel), Kiel, Germany.
⁵ Gastrointestinal Genetics Unit, Biodonostia Health Research Institute, San Sebastian, Spain.
⁶ Ikerbasque, Basque Foundation for Science, Bilbao, Spain.
⁷ Clinical Epidemiology Unit and Center for Molecular Medicine, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.

^# Contributed equally.

No abstract available

Keywords: carbohydrates; enteric bacterial microflora; genetics; irritable bowel syndrome.

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