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Papillomavirus Res. 2017 Dec;4:39-44. doi: 10.1016/j.pvr.2017.06.006. Epub 2017 Jun 19.

Prevalence and correlates of cervical HPV infection in a clinic-based sample of HIV-positive Hispanic women.

Author information

1
Department of Biostatistics and Epidemiology, Graduate School of Public Health, University of Puerto Rico, Medical Sciences Campus, San Juan, PR, United States; Cancer Control and Population Sciences Program, University of Puerto Rico Comprehensive Cancer Center, San Juan, PR, United States. Electronic address: ana.ortiz7@upr.edu.
2
Maternal-Infant Studies Center (CEMI), Department of OB-GYN, University of Puerto Rico School of Medicine, San Juan, PR, United States.
3
Doctoral Program in Public Health with specialty in Social Determinants of Health, Department of Social Sciences, Graduate School of Public Health, University of Puerto Rico Medical Sciences Campus, San Juan, PR, United States.
4
Department of Biostatistics and Epidemiology, Graduate School of Public Health, University of Puerto Rico, Medical Sciences Campus, San Juan, PR, United States.
5
Aids Research Laboratory, Ponce Health Sciences University, Ponce, PR, United States.
6
Maternal-Infant Studies Center (CEMI), Department of OB-GYN, University of Puerto Rico School of Medicine, San Juan, PR, United States; Department of OB-GYN, University of Puerto Rico School of Medicine, San Juan, PR, United States.

Abstract

OBJECTIVES:

Puerto Rico (PR), is the fifth highest jurisdiction of the United States of America (US) with respect to HIV prevalence and the leading in cervical cancer incidence. This cross-sectional study describes the prevalence and correlates of cervical HPV infection among a clinic-based sample of 302 women living with HIV/AIDS in PR.

METHODS:

Data collection included questionnaires, blood and cervical samples. Multivariable logistic regression models were used to estimate the magnitude of association (adjusted Prevalence odds ratio [aPOR]) between HPV cervical infection and other covariates.

RESULTS:

Mean age of participants was 40.3 years (± 10.3SD). The prevalence of HPV infection was 50.3%; 41.1% for low-risk types and 29.5% for high-risk types. Having ≥ 10 lifetime sexual partners (aPOR = 2.10, 95% CI:1.02-4.29), an abnormal Pap (aPOR = 3.58, 95% CI:1.93-6.62), active genital warts (aPOR = 3.45, 95% CI:1.60-7.42), and CD4 counts ≤ 200 (aPOR = 4.24, 95% CI: 1.67-10.78) were positively associated with any cervical HPV infection. Similar results were observed for HR HPV infection.

CONCLUSIONS:

A high burden of HPV co-infection exists among women living with HIV/AIDS in this population. Given the high incidence of HIV in PR and the higher risk of cervical cancer among women living with HIV/AIDS, HPV vaccination should be promoted in this population.

KEYWORDS:

Cervix; HIV; HPV; Hispanic women; Puerto Rico

PMID:
29179868
PMCID:
PMC5791754
DOI:
10.1016/j.pvr.2017.06.006
[Indexed for MEDLINE]
Free PMC Article

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