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Cir Esp. 2017 Dec;95(10):577-587. doi: 10.1016/j.ciresp.2017.08.007. Epub 2017 Oct 14.

Oncological results of the educational Rectal Cancer Project in Spain 10 years after its implementation.

[Article in English, Spanish]

Author information

1
Hospital Universitario Dr. Josep Trueta, Girona, España. Electronic address: acodinac.girona.ics@gencat.cat.
2
Hospital Universitario Bellvitge, Barcelona, España.
3
Hospital Universitario Vall d'Hebron, Barcelona, España.
4
Hospital Universitario Donostia, Donostia, España.
5
Hospital Universitario La Fe, Valencia, España.
6
Hospital Nisa, Valencia, España.
7
Instituto de Investigación Biomédica de Girona (IDIBGI), Girona, España.

Abstract

INTRODUCTION:

The objective of this observational, prospective, multicenter and multilevel study was to evaluate the oncological outcomes (local recurrence, metastasis and overall survival) of the Rectal Cancer Project of the Spanish Association of Surgeons (AEC) 10 years after its initiation, comparing the results with Scandinavian registries.

METHODS:

The AEC teaching project database includes 17,620 patients to date, of which 4,508 were operated on with a potentially curative resection between March 2006 and December 2010. All of them come from the first 59 hospitals included in the project, and therefore followed for at least 5 years, and are the subject of the present study.

RESULTS:

The cumulative incidence of local recurrence was 7.3 (95% CI: 8.2-6.5), metastasis 21.0 (CI 95%: 22.4-19.7) and overall survival 72.3 (CI 95%: 80.3-77.6). The multilevel regression analysis with the hospital variable as a random effect, showed a significant variation among the hospitals for the cancer outcome variables: general survival, local recurrence and metastasis (δ2=0.053).

CONCLUSIONS:

This study indicates that the results observed in the AEC' Rectal Cancer Project are inferior than those observed in the Scandinavian registries that we tried to emulate and that this is attributable to the variability of practice in some centers.

KEYWORDS:

Cáncer de recto; Local recurrence; Metastases; Metástasis; Overall survival; Recidiva local; Rectal cancer; Supervivencia global

PMID:
29037748
DOI:
10.1016/j.ciresp.2017.08.007
[Indexed for MEDLINE]

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