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Rev Col Bras Cir. 2017 Sep-Oct;44(5):435-443. doi: 10.1590/0100-69912017005003.

Prognostic factors and overall survival of breast cancer in the city of Goiania, Brazil: a population-based study.

[Article in English, Portuguese]

Author information

1
- Federal University of Goiás (HC/UFG), Mastology Program, Clinics Hospital, Goiânia, GO, Brazil.
2
- Goiás Association to Cancer Combat (ACCG), Araújo Jorge Hospital, Goiânia, GO, Brazil.
3
- Goiás Association to Cancer Combat (ACCG), Goiânia Population-based Cancer Registry, Goiânia, GO, Brazil.
4
- International Prevention Research Institute (iPRI), Senior Research, Lyon, Auvergne-Rhône-Alpes, France.
5
- AC Camargo Cancer Center, AC Camargo Hospital, São Paulo, SP, Brazil.

Abstract

OBJECTIVE:

to analyze the overall survival and prognostic factors of women with breast cancer in the city of Goiânia.

METHODS:

this is a retrospective, cross-sectional, observational study that included women with malignant neoplasms of the breast identified by the Goiânia Population-based Cancer Registry. The variables studied were age at diagnosis, tumor size, staging, axillary lymph node involvement, tumor grade, disease extent, hormone receptors, and c-erb-B2 oncoprotein. We performed overall survival analyzes of five and ten years.

RESULTS:

we included 2,273 patients in the study, with an overall survival of 72.1% in five years and 57.8% in ten years. In the multivariate analysis adjusted for tumor size, the factors that influenced the prognosis were axillary lymph nodes, histological grade, progesterone receptor, c erb B2, T staging and disease extension.

CONCLUSION:

overall survival in ten years is below that observed in other countries, and possibly reflects what happens with the majority of the Brazilian population. The prognostic factors found in this population follow the same international patterns.

PMID:
29019571
DOI:
10.1590/0100-69912017005003
[Indexed for MEDLINE]
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