The relation of somatotypes and stress response to central serous chorioretinopathy

Graefes Arch Clin Exp Ophthalmol. 2017 Dec;255(12):2307-2315. doi: 10.1007/s00417-017-3787-6. Epub 2017 Sep 5.

Abstract

Purpose: To investigate a possible relationship between central serous chorioretinopathy (CSC) and specific body types and compositions (somatotypes), and to examine the cortisol stress response among CSC patients of different somatotypes in comparison with healthy subjects.

Methods: Prospective case-control study. A group of 28 patients with a previous or current diagnosis of CSC was compared with a group of 26 healthy subjects. Anthropometric measurements were used to estimate somatotype ratings in all subjects. Serum cortisol was measured at rest and following a stress-inducing computerized test in order to estimate response to stress in both groups. The main outcome measures included somatotype categorization and the change in serum cortisol following stress in both groups.

Results: No significant difference in somatotype composition was found between the groups. There was no statistically significant difference between the groups in the elevation of cortisol following the stress-inducing test. The sample size was too small to exclude or find any significant difference between the different 13 subgroups of somatotype composition in the elevation of cortisol.

Conclusions: Our study did not show a typical somatotype related to CSC. While previous studies showed higher cortisol values in CSC patients, we did not see a higher elevation in blood cortisol following a stress response in this group in comparison with healthy subjects.

Keywords: Body composition; CSC; Central serous chorioretinopathy; Cortisol; Somatotypes; Stroop.

Publication types

  • Comparative Study

MeSH terms

  • Biomarkers / blood
  • Body Composition*
  • Case-Control Studies
  • Central Serous Chorioretinopathy / blood*
  • Central Serous Chorioretinopathy / diagnosis
  • Central Serous Chorioretinopathy / physiopathology
  • Choroid / pathology
  • Exercise Test
  • Female
  • Fluorescein Angiography
  • Fundus Oculi
  • Humans
  • Hydrocortisone / blood*
  • Male
  • Middle Aged
  • Prospective Studies
  • Retina / pathology
  • Somatotypes*
  • Stress, Physiological / physiology*
  • Stroop Test
  • Tomography, Optical Coherence

Substances

  • Biomarkers
  • Hydrocortisone