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J Pediatr Nurs. 2017 Jul - Aug;35:72-77. doi: 10.1016/j.pedn.2017.03.006. Epub 2017 Mar 28.

A Pilot Study Evaluating the Impact of an Adherence-promoting Intervention Among Nonadherent Youth With Inflammatory Bowel Disease.

Author information

1
Children's Mercy Kansas City, Kansas City, MO, USA. Electronic address: mhmaddux@cmh.edu.
2
Children's Mercy Kansas City, Kansas City, MO, USA.
3
Center for Adherence and Self-Management, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

Abstract

PURPOSE:

This study examined the feasibility and impact of a multicomponent adherence intervention among youth with Inflammatory Bowel Disease (IBD) who presented to clinic with poor adherence.

DESIGN AND METHODS:

Medical providers referred twelve adolescents for the intervention, who participated in 4 weekly visits with a caregiver aimed at improving adherence.

RESULTS:

Intervention session attendance was 100% and the intervention was rated as feasible and acceptable. Mean adherence increased 12% from baseline to post-intervention (p<0.01), and 6% from baseline to 1-month follow-up (p<0.025). A generalized linear model revealed significantly greater adherence from baseline to post-intervention (p<0.001), and from baseline to 1-month follow-up (p<0.01). Logistic Regression revealed a nearly 2:1 odds ratio during post-intervention when compared to the Baseline period (p<0.001).

CONCLUSIONS:

Findings suggest that the delivery of a multicompoment adherence intervention to poorly adherent youth with IBD can result in significant improvements in their adherence to oral medication.

PRACTICE IMPLICATIONS:

An intervention individually tailored to each family's unique adherence barriers is a feasible and promising treatment approach for improving medication adherence among nonadherent youth seen in clinical care.

KEYWORDS:

Adolescents; Inflammatory bowel disease; Intervention; Self-management

PMID:
28728772
DOI:
10.1016/j.pedn.2017.03.006
[Indexed for MEDLINE]

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