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Genome Biol. 2017 Jul 20;18(1):135. doi: 10.1186/s13059-017-1276-1.

Understanding the genetics behind complex human disease with large-scale iPSC collections.

Author information

1
Department of Biological Sciences, University of Notre Dame, Notre Dame, IN, 46556, USA.
2
Department of Biological Sciences, University of Notre Dame, Notre Dame, IN, 46556, USA. apanopou@nd.edu.
3
Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA, 92037, USA. belmonte@salk.edu.

Abstract

Three recent studies analyzing large-scale collections of human induced pluripotent stem cell lines provide valuable insight into how genetic regulatory variation affects cellular and molecular traits.

PMID:
28728561
PMCID:
PMC5520285
DOI:
10.1186/s13059-017-1276-1
[Indexed for MEDLINE]
Free PMC Article

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