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Cell Res. 2017 Jul;27(7):849-850. doi: 10.1038/cr.2017.71. Epub 2017 May 19.

Remote control of BBB: A tale of exosomes and microRNA.

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1
Zilkha Neurogenetic Institute and Department of Physiology and Neuroscience, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.

Abstract

Exosome-mediated intercellular communication has become an emerging field of human health and diseases. A recent study published by Cell Research reports that in zebrafish neurons can remotely regulate blood-brain barrier integrity by delivering miR-132 through secretion of exosomes.

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