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Mol Clin Oncol. 2016 Dec;5(6):783-785. doi: 10.3892/mco.2016.1044. Epub 2016 Oct 5.

Treatment of synchronous adenocarcinoma and lymphoma of the stomach: A case report.

Author information

1
NH Dartmouth Family Medicine Residency, Concord Hospital, Concord, NH 03301, USA; Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA; Division of Hematology/Oncology, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung 40705, Taiwan, R.O.C.
2
Department of Pathology and Laboratory Medicine, Taichung Veterans General Hospital, Taichung 40705, Taiwan, R.O.C.
3
Division of General Surgery, Department of Surgery, Taichung Veterans General Hospital, Taichung 40705, Taiwan, R.O.C.
4
Division of Hematology/Oncology, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung 40705, Taiwan, R.O.C.; Division of Transfusion Medicine, Department of Pathology and Laboratory Medicine, Taichung Veterans General Hospital, Taichung 40705, Taiwan, R.O.C.; Department of Medicine, Chung Shan Medical University, Taichung 40201, Taiwan, R.O.C.

Abstract

Gastric cancer is one of the leading causes of cancer-related mortality worldwide. The majority of gastric cancers are diagnosed at an advanced or metastatic stage, with a 5-year survival rate of ~5-20% and a median overall survival of <1 year. Synchronous occurrence of gastric adenocarcinoma and lymphoma is rare, and thus far there is no consensus regarding their management. We herein describe a case of synchronous gastric adenocarcinoma and diffuse large B-cell lymphoma in a patient with chronic hepatitis B and the treatment strategy. A literature review with the most up-to-date treatment options and their application in similar situations was also performed.

KEYWORDS:

diffuse large B-cell lymphoma; gastric adenocarcinoma; hepatitis B

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