Abstract
Specific features of LPO processes and antioxidant defense were studied in patients with polycystic ovarian syndrome (PCOS) and infertility. Changes in LPO processes in patients with PCOS were compensatory, which manifested in increased α-tocopherol and retinol concentrations and moderate decrease in superoxide dismutase activity. Intensification of prooxidant processes was found in the group of patients with infertility without PCOS. The observed changes necessitate differentiated approach to the treatment of these patients.
Keywords:
adaptation; antioxidant defense; lipid peroxidation; polycystic ovarian syndrome.
MeSH terms
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Adaptation, Physiological
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Adult
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Antioxidants / metabolism*
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Case-Control Studies
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Female
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Glutathione Disulfide / blood
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Humans
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Infertility, Female / blood*
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Infertility, Female / diagnosis
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Infertility, Female / pathology
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Lipid Peroxidation*
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Polycystic Ovary Syndrome / blood*
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Polycystic Ovary Syndrome / diagnosis
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Polycystic Ovary Syndrome / pathology
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Superoxide Dismutase / blood
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Thiobarbituric Acid Reactive Substances / metabolism
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Vitamin A / blood
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alpha-Tocopherol / blood
Substances
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Antioxidants
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Thiobarbituric Acid Reactive Substances
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Vitamin A
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Superoxide Dismutase
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alpha-Tocopherol
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Glutathione Disulfide