Evidences of autologous fat grafting for the treatment of keloids and hypertrophic scars

Rev Assoc Med Bras (1992). 2016 Dec;62(9):862-866. doi: 10.1590/1806-9282.62.09.862.

Abstract

Introduction: Since the 1980s, the use of autologous fat grafting has been growing in plastic surgery. Recently, this procedure has come to be used as a treatment for keloids and hypertrophic scars mainly due to the lack of satisfactory results with other techniques. So far, however, it lacks more consistent scientific evidence to recommend its use. The aim of this study was to review the current state of autologous fat grafting for the treatment of keloids and hypertrophic scars, their benefits and scientific evidences in the literature.

Method: A review in the Pubmed database was performed using the keywords "fat grafting and scar", "fat grafting and keloid scar" and "fat grafting and hypertrophic scar." Inclusion criteria were articles written in English and published in the last 10 years, resulting in 15 studies.

Results: These articles indicate that autologous fat grafting carried out at sites with pathological scars leads to a reduction of the fibrosis and pain, an increased range of movement in areas of scar contraction, an increase in their flexibility, resulting in a better quality of scars.

Conclusion: So far, evidences suggest that autologous fat grafting for the treatment of keloids and hypertrophic scars is associated with a better quality of scars, leading to esthetic and functional benefits. However, this review has limitations and these findings should be treated with reservations, since they mostly came from studies with low levels of evidence.

Publication types

  • Review

MeSH terms

  • Adipose Tissue / transplantation*
  • Cicatrix, Hypertrophic / metabolism
  • Cicatrix, Hypertrophic / surgery*
  • Humans
  • Keloid / metabolism
  • Keloid / surgery*
  • Pain, Postoperative / therapy
  • Treatment Outcome