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Nat Genet. 2016 Aug 30;48(9):978-9. doi: 10.1038/ng.3652.

Genomic landscape of the Greater Middle East.

Author information

1
Department of Molecular Biology and Genetics, Faculty of Science, Bilkent University, Ankara, Turkey.

Abstract

Study of the Greater Middle East (GME), home to approximately 10% of the world's population, has made invaluable contributions to the characterization of rare genetic disease, especially recessive conditions arising from the tradition of consanguinity and large families with multiple children. A new study now reports 1,111 unrelated exomes from the GME and provides a comprehensive view of genetic variation for enhanced discovery of disease-associated genes.

PMID:
27573686
DOI:
10.1038/ng.3652
[Indexed for MEDLINE]

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