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Cell. 2016 Jun 16;165(7):1572-1585. doi: 10.1016/j.cell.2016.05.043.

Stem Cells: A Renaissance in Human Biology Research.

Author information

1
Gene Expression Laboratory, The Salk Institute for Biological Studies, 10010 N. Torrey Pines Rd., La Jolla, CA 92037, USA; Universidad Católica San Antonio de Murcia (UCAM) Campus de los Jerónimos, 135, Guadalupe 30107, Murcia, Spain.
2
Gene Expression Laboratory, The Salk Institute for Biological Studies, 10010 N. Torrey Pines Rd., La Jolla, CA 92037, USA. Electronic address: belmonte@salk.edu.

Abstract

The understanding of human biology and how it relates to that of other species represents an ancient quest. Limited access to human material, particularly during early development, has restricted researchers to only scratching the surface of this inherently challenging subject. Recent technological innovations, such as single cell "omics" and human stem cell derivation, have now greatly accelerated our ability to gain insights into uniquely human biology. The opportunities afforded to delve molecularly into scarce material and to model human embryogenesis and pathophysiological processes are leading to new insights of human development and are changing our understanding of disease and choice of therapy options.

PMID:
27315475
DOI:
10.1016/j.cell.2016.05.043
[Indexed for MEDLINE]
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