Mesonephric (Wolffian) Pseudoendometrioid Carcinoma of the Broad Ligament, Arising From a Papillary Cystadenoma

Int J Surg Pathol. 2016 Oct;24(7):635-9. doi: 10.1177/1066896916644784. Epub 2016 Apr 20.

Abstract

This article describes the case of a 70-year-old woman with an adnexal cystadenocarcinoma located in the right broad ligament and displaying a striking resemblance to a well-differentiated endometrioid adenocarcinoma. The uniqueness of this pseudoendometrioid carcinoma lies in the fact that its mesonephric nature is revealed by the origin from a papillary cystadenoma of the broad ligament, where remnants of the mesonephric duct are seated, and the immunohistochemical profile, particularly a uniform negativity for estrogen and progesterone receptors, apical-luminal positivity for CD10, and strong nuclear positivity for GATA3.

Keywords: broad ligament; mesonephric carcinoma; papillary cystadenoma; pseudoendometrioid carcinoma.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Biomarkers, Tumor / analysis
  • Broad Ligament / pathology*
  • Carcinoma, Endometrioid / diagnosis
  • Cystadenocarcinoma / diagnosis*
  • Cystadenocarcinoma / pathology
  • Cystadenoma, Papillary / diagnosis*
  • Cystadenoma, Papillary / pathology
  • Diagnosis, Differential
  • Female
  • Humans
  • Immunohistochemistry

Substances

  • Biomarkers, Tumor