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Trends Endocrinol Metab. 2016 Jun;27(6):350-352. doi: 10.1016/j.tem.2016.03.014. Epub 2016 Mar 30.

Ketone Bodies Signal Opportunistic Food-Seeking Activity.

Author information

1
Regulatory Biology Laboratory, Salk Institute for Biological Studies, 10010, North Torrey Pines Road, La Jolla, CA 92037, USA.
2
Regulatory Biology Laboratory, Salk Institute for Biological Studies, 10010, North Torrey Pines Road, La Jolla, CA 92037, USA. Electronic address: satchin@salk.edu.

Abstract

Food-seeking activity at a predictable time of the day is one of the fundamental 'opportunistic behaviors' for survival. The neural and molecular basis for such anticipatory activity is not clearly understood. However, a new report shows that, after several hours of fasting, liver-derived ketone bodies have a key role in this behavior.

PMID:
27038664
PMCID:
PMC4903165
DOI:
10.1016/j.tem.2016.03.014
[Indexed for MEDLINE]
Free PMC Article

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