Keratolimbal autograft transplantation as a possible new treatment of Lisch epithelial corneal dystrophy

Arch Soc Esp Oftalmol. 2016 Jul;91(7):333-6. doi: 10.1016/j.oftal.2016.01.029. Epub 2016 Feb 28.
[Article in English, Spanish]

Abstract

Case report: The case concerns 64-year-old woman with visual acuity of 20/40 in the right eye. Slit-lamp examination revealed a grey, feathery corneal opacification with intraepithelial microcysts compatible with Lisch epithelial corneal dystrophy (LECD). It was treated with epithelial debridements, contact lenses and mitomycin C, but the opacification recurred within months. The removal of limbus sector and autologous limbal transplantation (KLAT) were used successfully without recurrence.

Conclusions: After removal of damaged limbus, KLAT should be considered as a treatment option for asymmetric LECD when other treatments have failed.

Keywords: Corneal dystrophy; Distrofia corneal; Distrofia de Lisch; Keratolimbal autograft transplantation; Lisch dystrophy; Trasplante autólogo de limbo.

Publication types

  • Case Reports

MeSH terms

  • Contact Lenses
  • Corneal Dystrophies, Hereditary / drug therapy
  • Corneal Dystrophies, Hereditary / surgery*
  • Corneal Transplantation / methods*
  • Debridement
  • Female
  • Humans
  • Limbus Corneae / surgery
  • Middle Aged
  • Mitomycin / therapeutic use
  • Recurrence
  • Transplantation, Autologous

Substances

  • Mitomycin

Supplementary concepts

  • Corneal Dystrophy, Lisch Epithelial