Follicular Mucinosis in a Male Adolescent with a History of Acute Myelogenous Leukemia and Graft-versus-Host Disease

Pediatr Dermatol. 2016 Jan-Feb;33(1):e34-5. doi: 10.1111/pde.12724. Epub 2015 Dec 8.

Abstract

Although many cases of follicular mucinosis are idiopathic, numerous others are associated with mycosis fungoides or, rarely, other neoplastic or inflammatory disorders. There are only three reported cases, all in adults, of follicular mucinosis arising in association with acute myelogenous leukemia, two of which involved mycosis fungoides-associated follicular mucinosis, including one case in which the patient had a preceding bone marrow transplant. We present the first reported case of follicular mucinosis arising in an adolescent with acute myelogenous leukemia and acute graft-versus-host disease after an allogeneic bone marrow transplantation.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Bone Marrow Transplantation / adverse effects*
  • Drug Therapy, Combination
  • Glucocorticoids / therapeutic use
  • Graft vs Host Disease / drug therapy
  • Graft vs Host Disease / etiology*
  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Leukemia, Myeloid, Acute / complications*
  • Leukemia, Myeloid, Acute / therapy
  • Male
  • Mucinosis, Follicular / etiology*
  • Skin / pathology
  • Tacrolimus / therapeutic use

Substances

  • Glucocorticoids
  • Immunosuppressive Agents
  • Tacrolimus