Format

Send to

Choose Destination
J Cutan Med Surg. 2016 May;20(3):221-7. doi: 10.1177/1203475415616073. Epub 2015 Nov 9.

Psoriasis and Smoking: A Systematic Literature Review and Meta-Analysis With Qualitative Analysis of Effect of Smoking on Psoriasis Severity.

Author information

1
Department of Medicine, Dermatology Service, St-Luc Hospital, Montreal, Quebec, Canada vincent.richer@umontreal.ca.
2
University of Montreal Hospital Research Center (CRCHUM), Notre-Dame Hospital, Montreal, Quebec, Canada.
3
Division of Dermatology, University of Toronto, Toronto, Ontario, Canada.
4
Sacré-Coeur Hospital of Montreal, University of Montreal, Montreal, Quebec, Canada.
5
Department of Dermatology and Skin Science, University of British Columbia, Vancouver, British Columbia, Canada.
6
Division of Rheumatology, University of Alberta, Edmonton, Alberta, Canada.
7
Division of Rheumatology, Department of Medicine, Western University of Canada, London, Ontario, Canada.
8
Lynde Dermatology, Markham, Ontario, Canada.
9
Department of Medicine, Rheumatic Disease Unit, Centre Hospitalier Universitaire de Québec (pavillon CHUL), Quebec City, Quebec, Canada.
10
Department of Medicine, Memorial University of Newfoundland, St John's, Newfoundland, Canada.
11
Department of Medicine, Rheumatic Disease Unit, Centre Hospitalier de l'Université de Montréal (CHUM) and Institut de Rhumatologie de Montréal, Montreal, Quebec, Canada.
12
Innovaderm Research, Montreal, Quebec, Canada.

Abstract

BACKGROUND:

Smoking has been associated with psoriasis prevalence and severity.

OBJECTIVE:

To evaluate prevalence of smoking in patients with psoriasis and to examine the relationship between smoking and psoriasis severity.

METHODS:

MEDLINE, EMBASE, and Cochrane databases (1960-2012) and conference proceedings (2010-2012) were systematically searched using keywords relevant to psoriasis and smoking. Controlled studies addressing psoriasis and smoking status were included. A meta-analysis for the relative risk of smoking in psoriasis patients was performed.

RESULTS:

Meta-analysis identified a significant association between smoking and psoriasis with a relative risk of 1.88 (95% CI, 1.66-2.13) for smoking in patients with psoriasis versus patients without psoriasis. Eight articles of 11 with data on smoking and psoriasis severity suggested that severity increases with smoking status.

CONCLUSIONS:

This literature review is in favor of a positive association between the prevalence of smoking and psoriasis as well as an association between smoking and severity of psoriasis.

KEYWORDS:

dermatology; psoriasis

PMID:
26553732
DOI:
10.1177/1203475415616073
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Atypon
Loading ...
Support Center