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Pediatr Radiol. 2016 Apr;46(4):575-8. doi: 10.1007/s00247-015-3488-4. Epub 2015 Nov 6.

Candida albicans pancreatitis in a child with cystic fibrosis post lung transplantation.

Author information

1
Mallinckrodt Institute of Radiology, Washington University School of Medicine, 510 S. Kingshighway Blvd., Campus Box 8131, St. Louis, MO, 63110, USA.
2
Department of Pathology, Washington University School of Medicine, St. Louis, MO, USA.
3
Division of Gastroenterology, Hepatology and Nutrition, Washington University School of Medicine, St. Louis, MO, USA.
4
Mallinckrodt Institute of Radiology, Washington University School of Medicine, 510 S. Kingshighway Blvd., Campus Box 8131, St. Louis, MO, 63110, USA. elizabeth.sheybani@gmail.com.

Abstract

We present a case of Candida albicans infection of a previously intact pancreas in a child with cystic fibrosis status post lung transplantation. Although Candida superinfection in necrotizing pancreatitis is not uncommon, this is a unique case of Candida infection of non-necrotic pancreatic parenchyma. This case presented a diagnostic dilemma for radiologists because it appeared virtually identical to acute interstitial edematous pancreatitis on imaging. Ultimately, endoscopic US-based biopsy was pursued for diagnosis. Although difficult to treat and compounded by the immunocompromised status of the child, the pancreatic infection improved with antifungal therapy.

KEYWORDS:

Candida albicans; Child; Cystic fibrosis; Fungus; Infection; Magnetic resonance imaging; Pancreas; Pancreatitis; Positron emission tomography

PMID:
26546567
DOI:
10.1007/s00247-015-3488-4
[Indexed for MEDLINE]

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