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Trends Biochem Sci. 2015 Dec;40(12):717-718. doi: 10.1016/j.tibs.2015.10.005. Epub 2015 Oct 31.

Synthesis at the Speed of Codons.

Author information

1
Department of Molecular Biology and Genetics, Johns Hopkins School of Medicine, Baltimore, MD, USA.
2
Department of Molecular Biology and Genetics, Johns Hopkins School of Medicine, Baltimore, MD, USA. Electronic address: ragreen@jhmi.edu.

Abstract

The possibility that different mRNA sequences encoding identical peptides are translated dissimilarly has long been of great interest. Recent work by Yu and co-workers provides striking evidence that mRNA sequences influence the rate of protein synthesis, and lends support to the emerging idea that mRNA sequence informs protein folding.

PMID:
26526516
DOI:
10.1016/j.tibs.2015.10.005
[Indexed for MEDLINE]

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