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Mamm Genome. 2015 Oct;26(9-10):448-55. doi: 10.1007/s00335-015-9600-0. Epub 2015 Sep 15.

The International Mouse Strain Resource (IMSR): cataloging worldwide mouse and ES cell line resources.

Author information

1
Mouse Genome Informatics, The Jackson Laboratory, Bar Harbor, ME, 04609, USA. janan.eppig@jax.org.
2
Mouse Genome Informatics, The Jackson Laboratory, Bar Harbor, ME, 04609, USA. howie.motenko@jax.org.
3
Mouse Genome Informatics, The Jackson Laboratory, Bar Harbor, ME, 04609, USA. joel.richardson@jax.org.
4
Mouse Genome Informatics, The Jackson Laboratory, Bar Harbor, ME, 04609, USA. beverly.richards-smith@jax.org.
5
Mouse Genome Informatics, The Jackson Laboratory, Bar Harbor, ME, 04609, USA. cynthia.smith@jax.org.

Abstract

The availability of and access to quality genetically defined, health-status known mouse resources is critical for biomedical research. By ensuring that mice used in research experiments are biologically, genetically, and health-status equivalent, we enable knowledge transfer, hypothesis building based on multiple data streams, and experimental reproducibility based on common mouse resources (reagents). Major repositories for mouse resources have developed over time and each has significant unique resources to offer. Here we (a) describe The International Mouse Strain Resource that offers users a combined catalog of worldwide mouse resources (live, cryopreserved, embryonic stem cells), with direct access to repository sites holding resources of interest and (b) discuss the commitment to nomenclature standards among resources that remain a challenge in unifying mouse resource catalogs.

PMID:
26373861
PMCID:
PMC4602064
DOI:
10.1007/s00335-015-9600-0
[Indexed for MEDLINE]
Free PMC Article

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