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Sci Transl Med. 2015 Aug 19;7(301):301fs34. doi: 10.1126/scitranslmed.aac9446.

Working stiff: how obesity boosts cancer risk.

Author information

1
Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI 53706, USA.
2
Developmental, Molecular, and Chemical Biology Department, Sackler School of Graduate Biomedical Sciences, Tufts University School of Medicine, Boston, MA 02111, USA. Molecular Oncology Research Institute, Tufts Medical Center, Boston, MA 02111, USA. Raymond and Beverly Sackler Convergence Laboratory, Tufts University School of Medicine, Boston, MA 02111, USA. charlotte.kuperwasser@tufts.edu.

Abstract

Obesity promotes breast cancer by enhancing the stiffness of breast adipose tissue through changes in the extracellular matrix (Seo et al., this issue).

PMID:
26290410
PMCID:
PMC4853750
DOI:
10.1126/scitranslmed.aac9446
[Indexed for MEDLINE]
Free PMC Article

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