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Clin Nucl Med. 2015 Aug;40(8):e411-4. doi: 10.1097/RLU.0000000000000836.

A Case of Massive Bone Metastases From Lung Cancer Detected Only by 18F-FDG PET/CT.

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From the *PET Center, Kofu Neurosurgical Hospital, Kofu City, Yamanashi Prefecture; †Department of Radiology, Tokyo Medical University Hachioji Medical Center; ‡Department of Radiology, Teikyo University School of Medicine, Teikyo University Hospital, Tokyo; and §Department of Radiology, Yamanashi University, Chuo City, Yamanashi Prefecture.


A 74-year-old man was diagnosed with small cell lung carcinoma in the left upper lobe. (18)F-FDG PET/CT showed multifocal strong abnormal uptakes in the axial skeleton and those of the primary lung tumor. CT failed to demonstrate the bony abnormalities. A subsequent (99m)Tc-MDP bone scintigraphy was also almost negative. It is important to note that bone metastasis may be undetectable by both CT and bone scintigraphy even if it is massive.

[Indexed for MEDLINE]

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