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Int J Gynecol Pathol. 2015 Mar;34(2):126-31. doi: 10.1097/PGP.0000000000000126.

Gastric signet-ring cell carcinoma metastasis to bilateral ovarian granulosa cell tumors.

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Departments of Pathology (L.S., Y.J., L.B.) General Surgery (Z.G.) Gynecology (J.L.), The Affiliated Hospital of Inner Mongolia Medical University Institute of Pathology and Pathophysiology (L.S., Y.J., L.B.), Inner Mongolia Medical University, Huhhot Department of Clinical Medicine Science (X.W.), China Pharmaceutical University, Nanjing, Jiangsu Province, China.


Tumor-to-tumor metastasis is a rare phenomenon. On the basis of our review of international literature, there have been 7 reports of tumor-to-tumor metastasis cases involving ovary neoplasms as the recipient. However, an ovarian granulosa cell tumor has not been reported to be a recipient. Here, we report the first case of gastric signet-ring cell carcinoma metastasis to a bilateral ovarian granulosa cell tumor. Awareness of this phenomenon is important to avoid incorrect diagnoses when encountering unusual morphologic features in ovarian granulosa cell tumors.

[Indexed for MEDLINE]

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