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Items: 16


Identification and validation of midbrain Kcnq4 regulation of heavy alcohol consumption in rodents.

McGuier NS, Rinker JA, Cannady R, Fulmer DB, Jones SR, Hoffman M, Mulholland PJ.

Neuropharmacology. 2018 Aug;138:10-19. doi: 10.1016/j.neuropharm.2018.05.020. Epub 2018 May 25.


Chronic Alcohol, Intrinsic Excitability, and Potassium Channels: Neuroadaptations and Drinking Behavior.

Cannady R, Rinker JA, Nimitvilai S, Woodward JJ, Mulholland PJ.

Handb Exp Pharmacol. 2018;248:311-343. doi: 10.1007/164_2017_90. Erratum in: Handb Exp Pharmacol. 2018;248:619.


Promising pharmacogenetic targets for treating alcohol use disorder: evidence from preclinical models.

Rinker JA, Mulholland PJ.

Pharmacogenomics. 2017 Apr;18(6):555-570. doi: 10.2217/pgs-2016-0193. Epub 2017 Mar 27. Review.


Prefrontal Cortex KCa2 Channels Regulate mGlu5-Dependent Plasticity and Extinction of Alcohol-Seeking Behavior.

Cannady R, McGonigal JT, Newsom RJ, Woodward JJ, Mulholland PJ, Gass JT.

J Neurosci. 2017 Apr 19;37(16):4359-4369. doi: 10.1523/JNEUROSCI.2873-16.2017. Epub 2017 Mar 20.


Kv7 channels in the nucleus accumbens are altered by chronic drinking and are targets for reducing alcohol consumption.

McGuier NS, Griffin WC 3rd, Gass JT, Padula AE, Chesler EJ, Mulholland PJ.

Addict Biol. 2016 Nov;21(6):1097-1112. doi: 10.1111/adb.12279. Epub 2015 Jun 23.


Differential potassium channel gene regulation in BXD mice reveals novel targets for pharmacogenetic therapies to reduce heavy alcohol drinking.

Rinker JA, Fulmer DB, Trantham-Davidson H, Smith ML, Williams RW, Lopez MF, Randall PK, Chandler LJ, Miles MF, Becker HC, Mulholland PJ.

Alcohol. 2017 Feb;58:33-45. doi: 10.1016/j.alcohol.2016.05.007. Epub 2016 Jun 27.


FMRP Mediates Chronic Ethanol-Induced Changes in NMDA, Kv4.2, and KChIP3 Expression in the Hippocampus.

Spencer KB, Mulholland PJ, Chandler LJ.

Alcohol Clin Exp Res. 2016 Jun;40(6):1251-61. doi: 10.1111/acer.13060. Epub 2016 May 5. Erratum in: Alcohol Clin Exp Res. 2016 Sep;40(9):2021.


KCNN Genes that Encode Small-Conductance Ca2+-Activated K+ Channels Influence Alcohol and Drug Addiction.

Padula AE, Griffin WC 3rd, Lopez MF, Nimitvilai S, Cannady R, McGuier NS, Chesler EJ, Miles MF, Williams RW, Randall PK, Woodward JJ, Becker HC, Mulholland PJ.

Neuropsychopharmacology. 2015 Jul;40(8):1928-39. doi: 10.1038/npp.2015.42. Epub 2015 Feb 9.


Neuroplasticity of A-type potassium channel complexes induced by chronic alcohol exposure enhances dendritic calcium transients in hippocampus.

Mulholland PJ, Spencer KB, Hu W, Kroener S, Chandler LJ.

Psychopharmacology (Berl). 2015 Jun;232(11):1995-2006. doi: 10.1007/s00213-014-3835-4. Epub 2014 Dec 17.


Novel anticonvulsants for reducing alcohol consumption: A review of evidence from preclinical rodent drinking models.

Padula AE, McGuier NS, Griffin WC, Lopez MF, Becker HC, Mulholland PJ.

OA Alcohol. 2013 Feb 1;1(1):2.


K(Ca)2 channels: novel therapeutic targets for treating alcohol withdrawal and escalation of alcohol consumption.

Mulholland PJ.

Alcohol. 2012 Jun;46(4):309-15. doi: 10.1016/j.alcohol.2011.11.002. Epub 2012 Mar 30. Review.


Small conductance calcium-activated potassium type 2 channels regulate alcohol-associated plasticity of glutamatergic synapses.

Mulholland PJ, Becker HC, Woodward JJ, Chandler LJ.

Biol Psychiatry. 2011 Apr 1;69(7):625-32. doi: 10.1016/j.biopsych.2010.09.025. Epub 2010 Nov 5.


Inhibition of glutamate transporters couples to Kv4.2 dephosphorylation through activation of extrasynaptic NMDA receptors.

Mulholland PJ, Chandler LJ.

Neuroscience. 2010 Jan 13;165(1):130-7. doi: 10.1016/j.neuroscience.2009.10.024. Epub 2009 Oct 20.


Sizing up ethanol-induced plasticity: the role of small and large conductance calcium-activated potassium channels.

Mulholland PJ, Hopf FW, Bukiya AN, Martin GE, Liu J, Dopico AM, Bonci A, Treistman SN, Chandler LJ.

Alcohol Clin Exp Res. 2009 Jul;33(7):1125-35. doi: 10.1111/j.1530-0277.2009.00936.x. Epub 2009 Apr 9. Review.


Ethanol disrupts NMDA receptor and astroglial EAAT2 modulation of Kv2.1 potassium channels in hippocampus.

Mulholland PJ, Carpenter-Hyland EP, Woodward JJ, Chandler LJ.

Alcohol. 2009 Feb;43(1):45-50. doi: 10.1016/j.alcohol.2008.10.001.


Glutamate transporters regulate extrasynaptic NMDA receptor modulation of Kv2.1 potassium channels.

Mulholland PJ, Carpenter-Hyland EP, Hearing MC, Becker HC, Woodward JJ, Chandler LJ.

J Neurosci. 2008 Aug 27;28(35):8801-9. doi: 10.1523/JNEUROSCI.2405-08.2008.

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