Format

Send to

Choose Destination
Cell Res. 2015 Mar;25(3):271-2. doi: 10.1038/cr.2015.11. Epub 2015 Jan 30.

Regenerative medicine: targeted genome editing in vivo.

Author information

1
National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
2
Gene Expression Laboratory, Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.
3
Beijing Hospital of the Ministry of Health, Beijing 100730, China.
4
1] National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China [2] Beijing Institute for Brain Disorders, Beijing 100069, China [3] Center for Molecular and Translational Medicine, Beijing 100101, China.

Abstract

The CRISPR/Cas system has proven to be a powerful gene editing tool both in vitro and in vivo. A recent flurry of studies of in vivo gene editing using the CRISPR/Cas system bring bright prospects in creating animal models and targeted gene therapy of human genetic diseases.

PMID:
25633595
PMCID:
PMC4349243
DOI:
10.1038/cr.2015.11
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Nature Publishing Group Icon for PubMed Central
Loading ...
Support Center