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J Cosmet Laser Ther. 2014 Dec;16(6):324-7. doi: 10.3109/14764172.2014.957218. Epub 2014 Sep 25.

Comparative efficacy of intense pulsed light for different erythema associated with rosacea.

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Department of Dermatology, 306 Hospital of PLA , Beijing , P. R. China.



To compare the efficacy of intense pulsed light (IPL) (540-950 nm) in treating different erythema associated with rosacea.


Thirty-two patients with erythematotelangiectatic rosacea (ETR) (n = 16) and papulopustular rosacea (PPR, n = 16) were recruited. Three treatments of IPL (540-950 nm) were administered on the face at 3-week intervals. Clinical improvement in erythema was independently assessed by two dermatologists using a quartile grading scale [0, ≤ 25% improvement (poor); 1, 26-50% improvement (fair); 2, 51-75% improvement (good); and 3, 76-100% improvement (excellent)]. Patient satisfaction was evaluated using a 10-point visual analog scale (VAS: 0, lowest; and 10, highest).


Thirty patients were involved in this study. All patients showed improvement in erythema after three sessions of IPL (540-950 nm) treatment. Based on physician's assessment, the overall clinical improvement in PPR group was significantly higher (mean ± SD of PPR group, 2.167 ± 0.748 vs. ETR group, 1.400 ± 0.541; P = 0.003) and patient satisfaction was also higher in PPR group (mean ± SD of PPR group, 6.867 ± 1.457 vs. ETR group, 5.600 ± 1.502; P = 0.026). The proportion of patients showing > 75% clinical improvement among PPR group was also higher than that among ETR group (5/15 and 0/15, respectively; P = 0.021). Side effects were minimal and transient (erythema and/or edema) for patients.


IPL (540-950 nm) is a safe and effective treatment for rosacea-associated erythema, especially for perilesional erythema.


erythema; intense pulsed light; rosacea

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