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Trends Biochem Sci. 2014 Oct;39(10):447-56. doi: 10.1016/j.tibs.2014.06.006. Epub 2014 Aug 1.

The growth-defense pivot: crisis management in plants mediated by LRR-RK surface receptors.

Author information

1
Gregor Mendel Institute, Austrian Academy of Sciences, Vienna Biocenter, Dr. Bohr-Gasse 3, 1030 Vienna, Austria.
2
Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Howard Hughes Medical Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
3
Plant Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA; Division of Biology, University of California, San Diego, Gilman Drive, La Jolla, CA 92037, USA.
4
Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Howard Hughes Medical Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Microbiology and Immunology, Coker Hall # 3280, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Curriculum in Genetics, Coker Hall # 3280, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Carolina Center for Genome Sciences, Coker Hall # 3280, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. Electronic address: dangl@email.unc.edu.
5
Howard Hughes Medical Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Plant Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA. Electronic address: chory@salk.edu.

Abstract

Plants must adapt to their environment and require mechanisms for sensing their surroundings and responding appropriately. An expanded family of more than 200 leucine-rich repeat (LRR) receptor kinases (LRR-RKs) transduces fluctuating and often contradictory signals from the environment into changes in nuclear gene expression. Two LRR-RKs, BRASSINOSTEROID INSENSITIVE 1 (BRI1), a steroid receptor, and FLAGELLIN SENSITIVE 2 (FLS2), an innate immune receptor that recognizes bacterial flagellin, act cooperatively to partition necessary growth-defense trade-offs. BRI1 and FLS2 share common signaling components and slightly different activation mechanisms. BRI1 and FLS2 are paradigms for understanding the signaling mechanisms of LRR-containing receptors in plants.

KEYWORDS:

LRR-RKs; cell surface signaling; crosstalk; innate immunity; plant growth; trade-offs

PMID:
25089011
PMCID:
PMC4177940
DOI:
10.1016/j.tibs.2014.06.006
[Indexed for MEDLINE]
Free PMC Article

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