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Eur J Clin Nutr. 2015 Feb;69(2):173-8. doi: 10.1038/ejcn.2014.138. Epub 2014 Jul 16.

Effect of 12-month intervention with lipid-based nutrient supplements on physical activity of 18-month-old Malawian children: a randomised, controlled trial.

Author information

1
University of Tampere School of Medicine, Department for International Health, Tampere, Finland.
2
1] Duke-National University of Singapore Graduate Medical School, Centre for Quantitative Medicine, Singapore, Singapore [2] Singapore Clinical Research Institute, Department of Biostatistics, Singapore, Singapore.
3
University of California, Davis, Department of Nutrition, Davis, CA, USA.
4
University of Malawi College of Medicine, Department of Community Health, Blantyre, Malawi.
5
University of California Davis, Department of Agricultural and Resource Economics, Davis, CA, USA.
6
1] University of Tampere School of Medicine, Department for International Health, Tampere, Finland [2] Tampere University Hospital, Department of Paediatrics, Tampere, Finland.

Abstract

BACKGROUND/OBJECTIVES:

This study measured the effects of dietary supplementation with lipid-based nutrient supplements (LNSs) on 18-month-old children's physical activity.

SUBJECTS/METHODS:

In a randomised, controlled, outcome-assessor blinded trial 1932 six-month-old children from Malawi received one of five interventions daily from 6-18 months of age: 10-g milk-LNS, 20-g milk-LNS, 20-g non-milk-LNS, 40-g milk-LNS or 40-g non-milk-LNS, or received no intervention in the same period (control). The control group received delayed intervention with corn-soy blend from 18-30 months. Physical activity was measured over 1 week by ActiGraph GT3X+ accelerometer at 18 months. Main outcome was mean vector magnitude accelerometer counts/15 s. Analyses were restricted to children with valid accelerometer data on at least 4 days with minimum 6 h of wearing time per day.

RESULTS:

Of the 1435 children recruited to this substudy, 1053 provided sufficient data for analysis. The mean (s.d.) vector magnitude accelerometer counts in the total sample were 307 (64). The difference (95% CI) in mean accelerometer counts, compared with the control group, was 8 (-6 to 21, P=0.258) in 10-g milk-LNS, 3 (-11 to 17, P=0.715) in 20-g milk-LNS, 5 (-8 to 19, P=0.445) in 20-g non-milk-LNS, 10 (-3 to 23, P=0.148) in 40-g milk-LNS and 2 (-12 to 16, P=0.760) in 40-g non-milk-LNS groups.

CONCLUSIONS:

Provision of 10-40 g doses of LNS daily for 12 months did not increase physical activity of Malawian toddlers.

PMID:
25028082
DOI:
10.1038/ejcn.2014.138
[Indexed for MEDLINE]

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