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FEMS Microbiol Lett. 2014 Aug;357(2):157-63. doi: 10.1111/1574-6968.12515. Epub 2014 Jul 14.

Bifidobacterium animalis ssp. lactis BI07 modulates the tumor necrosis factor alpha-dependent imbalances of the enterocyte-associated intestinal microbiota fraction.

Author information

1
Department of Pharmacy and Biotechnology, University of Bologna, Bologna, Italy.

Abstract

Using a previously developed in vitro model to characterize the enterocyte-adherent microbiota fraction, we explored the potential of the probiotic strain Bifidobacterium animalis ssp. lactis BI07 to modulate the inflammation-dependent dysbioses of the enterocyte-adherent microbiota from 12 healthy human donors. According to our findings, B. animalis ssp. lactis BI07 is effective in limiting the increase of pro-inflammatory pathobionts on the inflamed mucosal site, supporting the recovery of a mutualistic community.

KEYWORDS:

Bifidobacterium lactis; gut inflammation; gut microbiota; probiotics

PMID:
24964713
DOI:
10.1111/1574-6968.12515
[Indexed for MEDLINE]
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