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Nat Rev Gastroenterol Hepatol. 2014 Jul;11(7):398-9. doi: 10.1038/nrgastro.2014.91. Epub 2014 Jun 17.

Coeliac disease: noncoeliac gluten sensitivity--food for thought.

Author information

1
Department of Gastroenterology, Royal Hallamshire Hospital, Glossop Road, Sheffield S10 2JF, UK.
2
Department of Neurosciences, Royal Hallamshire Hospital, Glossop Road, Sheffield S10 2JF, UK.

Abstract

Patients with noncoeliac gluten sensitivity (NCGS) can experience a range of gastrointestinal and extraintestinal symptoms. A study has now demonstrated that gluten is independently associated with depression in patients with NCGS. NCGS-associated depression might share similar pathophysiological mechanisms to other neurological manifestations observed in gluten-related disorders, such as ataxia and encephalopathy.

PMID:
24935422
DOI:
10.1038/nrgastro.2014.91
[Indexed for MEDLINE]
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