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J Comput Assist Tomogr. 2014 Sep-Oct;38(5):797-801. doi: 10.1097/RCT.0000000000000114.

Computed tomography (CT) venography with dual-energy CT: low tube voltage and dose reduction of contrast medium for detection of deep vein thrombosis.

Author information

1
From the Department of Radiology, University of Yamanashi, Yamanashi, Japan.

Abstract

OBJECTIVES:

To assess whether low-dose contrast medium and low-tube voltage computed tomography (CT) venography can be used for clinical diagnosis.

METHODS:

This prospective study included 63 patients who were randomized into 3 groups and administered contrast medium of either 600, 500, or 400 mg of iodine per kilogram (mgI/kg). All patients underwent dual-energy CT at either 80 or 135 kilovolt (peak) (kV[p]). Control images (120 kV[p]) were acquired from them and were compared with 80-kV(p) images. The mean CT values of the bilateral femoral and popliteal veins were compared.

RESULTS:

The mean CT values of the 80-kV(p) images were significantly higher than 120-kV(p) images for all doses. No significant difference was observed for the CT values of the 80-kV(p) images with the 400-mgI/kg dose and the control images (600 mgI/kg at 120 kV[p]).

CONCLUSIONS:

Low tube voltage enabled a reduction of contrast medium to 400 mgI/kg for CT venography.

PMID:
24887576
DOI:
10.1097/RCT.0000000000000114
[Indexed for MEDLINE]

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