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Chem Biodivers. 2014 Jan;11(1):133-9. doi: 10.1002/cbdv.201300115.

Cytotoxic polyphenols from a sponge-associated fungus Aspergillus versicolor Hmp-48.

Author information

1
Institute of Applied Ecology, Chinese Academy of Sciences, Shenyang 110016, P. R. China, (phone: +86-88087740); School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, P. R. China.

Abstract

A new dibenzo[1,4]dioxin 1, and two new prenylated diphenyl ethers, 2 and 3, together with six known compounds, 4-9, were isolated from a sponge-associated fungus Aspergillus versicolor Hmp-F48 by bioactivity-guided fractionation. Their structures were elucidated by 1D- and 2D-NMR, and MS analyses. The compounds showed potent cell growth inhibitory activities against HL-60 cell line.

KEYWORDS:

Aspergillus versicolor; Dibenzo[1,4]dioxin; Fungus; Sponges

PMID:
24443433
DOI:
10.1002/cbdv.201300115
[Indexed for MEDLINE]

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