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J Clin Neurosci. 2014 Jul;21(7):1250-1. doi: 10.1016/j.jocn.2013.09.018. Epub 2013 Nov 26.

Leptomeningeal carcinomatosis from breast cancer treated with intrathecal topotecan with concomitant intravenous eribulin.

Author information

  • 1Boston University, Boston, MA, USA.
  • 2University of Chicago, Department of Medicine, Section of Hematology & Oncology, Chicago, IL, USA.
  • 3University of Chicago, Department of Neurology, 5841 South Maryland Avenue, MC 2030, Chicago, IL 60637, USA. Electronic address: rlukas@neurology.bsd.uchicago.edu.

Abstract

We present a patient with leptomeningeal carcinomatosis from breast cancer treated with intrathecal topotecan and intravenous eribulin. The regimen was well tolerated and provided clinical stability in a patient with progression on a prior intrathecal chemotherapy regimen.

KEYWORDS:

Breast neoplasms; Eribulin; Intrathecal; Meningeal carcinomatosis; Topotecan

PMID:
24412296
DOI:
10.1016/j.jocn.2013.09.018
[PubMed - indexed for MEDLINE]
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