Outcome of conventional treatment for adult amblyopia

Jpn J Ophthalmol. 2014 Jan;58(1):26-32. doi: 10.1007/s10384-013-0279-z. Epub 2013 Oct 26.

Abstract

Purpose: To ascertain whether conventional treatment can improve visual function in adults with amblyopia.

Methods: Sixteen patients aged 21-67 years old were instructed to wear glasses for refractive correction and to patch the non-amblyopic eye for at least 1 h per day. Visual acuity, measured with crowded optotypes for distance and near acuity, was checked every 3 months, and followed for a mean (SD) of 14.1 (4.2) months. Prognostic factors related to the subsequent results, an improvement of 3 or more lines logMAR in distance visual acuity, were evaluated.

Results: Of 16 patients, 5 (31 %) improved 3 or more lines of distance and 5 (31 %) in near acuity. The mean improvement in distance was 2.4 lines logMAR (95 % CI 1.4-3.5) and 2.4 lines logMAR for near acuity (95 % CI 1.5-3.3). Patients aged under 45 years (p = 0.0357) and with severe amblyopia (p = 0.0337), defined as a corrected distance visual acuity of worse than -0.699 logMAR, were associated with a good response.

Conclusions: Conventional treatment may improve the visual acuity of amblyopic eyes even in adult patients.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Amblyopia / physiopathology
  • Amblyopia / therapy*
  • Bandages
  • Depth Perception / physiology*
  • Eyeglasses*
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Neuronal Plasticity / physiology
  • Sensory Deprivation*
  • Treatment Outcome
  • Visual Acuity / physiology*
  • Visual Cortex / physiology
  • Young Adult