Incidence of strabismus and amblyopia in preverbal children previously diagnosed with pseudoesotropia

Am Orthopt J. 2013:63:103-6. doi: 10.3368/aoj.63.1.103.

Abstract

Background and purpose: We previously reported that 12% of children under age 3 diagnosed with pseudoesotropia without significant refractive error later developed strabismus or mild refractive amblyopia. Mohan and Sharma recently reported on fifty-one patients with pseudoesotropia and hyperopia and noted that esotropia developed in 53.9% of the children with >1.50 D of hypermetropia compared to 2.6% of those who had ≤1.50 D hypermetropia, implying a low risk of esotropia unless hyperopia was greater than 1.50 D on initial exam. We reviewed our data to see if we had similar findings in our patients.

Method: Medical records between January 1, 2001, and February 26, 2010, were reviewed retrospectively. Three hundred ninety-four patients diagnosed with pseudoesotropia with an otherwise normal examination were reviewed, and 253 with follow-up were analyzed.

Results: Forty-six children were 36 months or older at initial presentation; none developed strabismus; 207 children were <36 months at initial presentation; twenty-two children (11%) were later found to have strabismus. Seventy-eight of these children had hyperopia > 1.50 D; eight children (10%) later developed strabismus. One hundred twenty-nine children had hyperopia ≤ 1.50 D, and fourteen (11%) developed strabismus. Our analysis showed an equal risk of strabismus developing in pseudoesotropia patients under age 3 with greater or less than 1.50 D of hyperopia.

Conclusion: There is a significant risk of esotropia developing in children under three diagnosed with pseudoesotropia. Hyperopia less than 1.50 D, does not obviate the need for careful follow-up.

Keywords: amblyopia; esotropia; pseudoesotropia; refractive error.

Publication types

  • Comparative Study

MeSH terms

  • Amblyopia / complications
  • Amblyopia / diagnosis
  • Amblyopia / epidemiology*
  • Child, Preschool
  • Diagnosis, Differential
  • Esotropia / complications
  • Esotropia / diagnosis*
  • Esotropia / epidemiology
  • Female
  • Humans
  • Incidence
  • Male
  • Pennsylvania / epidemiology
  • Retrospective Studies
  • Risk Factors
  • Visual Acuity