[Corneal transplant in a second level hospital. A survival analysis]

Gac Med Mex. 2013 Jul-Aug;149(4):425-30.
[Article in Spanish]

Abstract

Objective: To determine the long-term corneal graft survival in patients of General Hospital Dr. Miguel Silva.

Materials and methods: This was a retrospective cohort study. Records from patients who underwent corneal transplant surgery at General Hospital Dr. Miguel Silva were analyzed. The percentages of graft failure were obtained. Kaplan-Meier survival analysis was performed to evaluate the long-term cumulative probability of graft non-rejection in all patients according to diagnosis.

Results: Overall, 71.9% (CI 95%: 64.8-78.9) of the patients did not have any graft rejections, and 12.5% (CI 95%: 7-18) required a regraft and were considered graft failures. Patients with posttraumatic leucoma had a cumulative probability of non-rejection of 100%. Subjects with keratoconus had a 65% likelihood of non-rejection after 40 months of follow-up. The likelihood of non-rejection was greater than 80% at 100 months of follow-up in pseudophakic bullous keratopathy patients and 60% at 20 months of follow-up in inactive herpetic leucoma patients.

Conclusions: Posttraumatic leucoma patients had the greatest cumulative survival probability compared with postherpetic leucoma patients and other patient groups.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Cohort Studies
  • Corneal Transplantation* / mortality
  • Female
  • Humans
  • Male
  • Retrospective Studies
  • Secondary Care Centers
  • Survival Analysis